New approaches for combined therapy of Hodgkin's lymphoma

Abstract

Based on the treatment results of 819 patients we formulated new approaches for combined treatment of Hodgkin’s lymphoma stages I-IV. It was constructed a simplified prognostic model and developed new alternating chemotherapy regimens. We demonstrated the possibility of reducing the number of courses of chemotherapy to 4 in poor prognosis cases and the dispensability of achieving a complete effect after execution of medication period, emphasized the important role of a subradical programme, the expediency of zonal reduction offields, and the necessity of irradiating the whole volume of a lymphatic collector in the doses not greater than 30 Gy.The above approaches offer prospects for treatment of Hodgkin’s lymphoma.

Keywords

• hodgkin’s disease
• hodgkin’s lymphoma
• combined treatment
• zonal field reduction