Data on the evaluation of FGF2 gene expression in Colorectal Cancer
Helena Caiado,
Natércia Conceição,
Daniel Tiago,
Ana Marreiros,
Susana Vicente,
Jose Luis Enriquez,
Ana Margarida Vaz,
Artur Antunes,
Horácio Guerreiro,
Paulo Caldeira,
M. Leonor Cancela
Affiliations
Helena Caiado
ProRegeM PhD Programme in Mechanisms of disease and regenerative medicine, University of Algarve, Faro, 8005-139, Portugal; Center of Marine Sciences (CCMAR), University of Algarve, Faro, 8005-139, Portugal; Department of Biomedical Sciences and Medicine, University of Algarve, Faro, 8005-139, Portugal
Natércia Conceição
Center of Marine Sciences (CCMAR), University of Algarve, Faro, 8005-139, Portugal; Department of Biomedical Sciences and Medicine, University of Algarve, Faro, 8005-139, Portugal; Algarve Biomedical Center, University of Algarve, Faro, 8005-139, Portugal; Corresponding author.
Daniel Tiago
Center of Marine Sciences (CCMAR), University of Algarve, Faro, 8005-139, Portugal; Residency at University Hospital of Algarve, Faro 8000-386
Ana Marreiros
Department of Biomedical Sciences and Medicine, University of Algarve, Faro, 8005-139, Portugal; Algarve Biomedical Center, University of Algarve, Faro, 8005-139, Portugal
Susana Vicente
Pathology Department, University Hospital of Algarve, Faro, 8000-386
Jose Luis Enriquez
Pathology Department, University Hospital of Algarve, Faro, 8000-386
Ana Margarida Vaz
Gastroenterology Department, University Hospital of Algarve, Faro, 8000-386
Artur Antunes
Gastroenterology Department, University Hospital of Algarve, Faro, 8000-386
Horácio Guerreiro
Gastroenterology Department, University Hospital of Algarve, Faro, 8000-386
Paulo Caldeira
Department of Biomedical Sciences and Medicine, University of Algarve, Faro, 8005-139, Portugal; Gastroenterology Department, University Hospital of Algarve, Faro, 8000-386
M. Leonor Cancela
Center of Marine Sciences (CCMAR), University of Algarve, Faro, 8005-139, Portugal; Department of Biomedical Sciences and Medicine, University of Algarve, Faro, 8005-139, Portugal; Algarve Biomedical Center, University of Algarve, Faro, 8005-139, Portugal; Centre for Biomedical Research, University of Algarve, Faro 8000-139, Portugal; Corresponding author.
The data presented in this article is related with the research paper entitled “Evaluation of MGP gene expression in colorectal cancer”, available on Gene journal [1]. From all the transcription factors known to regulate MGP, FGF2 is the most described in colon adenocarcinoma and colon tumor cell lines, where it was shown to: i) contribute for the invasiveness potential; and ii) promote proliferation and survival of colorectal cancer cells. These in vitro studies pose the hypothesis that FGF2 associated signaling pathways could be promoting the regulation of others genes, such as MGP, that may lead to tumor progression which ultimately could result in poor prognosis in colon adenocarcinoma.
