Nature Communications (Apr 2020)

Antibacterial effects of nanopillar surfaces are mediated by cell impedance, penetration and induction of oxidative stress

  • J. Jenkins,
  • J. Mantell,
  • C. Neal,
  • A. Gholinia,
  • P. Verkade,
  • A. H. Nobbs,
  • B. Su

DOI
https://doi.org/10.1038/s41467-020-15471-x
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 14

Abstract

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Synthetic nanopillars resembling the wing surface of certain insects display antibacterial activities. Here, Jenkins et al. show that these activities do not necessarily require bacterial lysis, and may be mediated by oxidative stress induced by deformation of the bacterial cell envelope.