Nature Communications (Nov 2017)

Structure and functional dynamics of the mitochondrial Fe/S cluster synthesis complex

  • Michal T. Boniecki,
  • Sven A. Freibert,
  • Ulrich Mühlenhoff,
  • Roland Lill,
  • Miroslaw Cygler

DOI
https://doi.org/10.1038/s41467-017-01497-1
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 15

Abstract

Read online

Fe/S clusters are synthesized by the mitochondrial iron-sulfur cluster assembly (ISC) machinery. Here the authors combine crystallography and small angle X-ray scattering measurements to structurally characterize the core ISC complex and give functional insights into eukaryotic Fe/S cluster synthesis.