Bis-Hydrazonoyl chloride as precursors

Abstract

A series of novel bis-pyrazole, bis(imidazo[1,2-b][1,2,4]triazole) and bis(imidazo[1,2-a]benzimidazole) derivatives were synthesized via bis-hydrazonoyl chloride. Structures of the synthesized compounds were elucidated by means of IR, 1H NMR and mass spectral data. The biological activity of the newly synthesized compounds was examined and some of them were found to possess antimicrobial and anticancer activities.

Keywords

• bis-Hydrazonoyl chloride
• bis-Pyrazoles
• Nucleophilic addition reaction
• Antimicrobial activity
• Anticancer activity