Virus-induced modulation of apoptotic cell death program

Abstract

Data of native and foreign authors concerning presence of several adaptive mechanisms in viruses which allow them to influence on key moments of apoptosis process are presented in the paper. Viral destructive action, intensity and efficacy of immune reactions and hence clinical manifestations of infectious process depend on virus-induced modulation of programmed cellular death. Influence of viruses on the program of apoptosis is established to be the basic one in forming viral persistence.

Keywords

• апоптоз
• вирусы
• персистенция
• модуляция апоптоза