Reproductive Medicine and Biology (Jan 2023)

The impact of the embryo banking on the cumulative live birth rate in women with poor ovarian response according to the Bologna criteria

  • Qiu Lin Ge,
  • Xiao Ming Teng,
  • Miao Xin Chen,
  • Kun Ming Li,
  • Ernest Hung Yu Ng,
  • Zhi Qin Chen

DOI
https://doi.org/10.1002/rmb2.12533
Journal volume & issue
Vol. 22, no. 1
pp. n/a – n/a

Abstract

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Abstract Purpose To evaluate the impact of embryo banking on the cumulative live birth rate (CLBR) and the time to live birth (TTLB) in poor ovarian responders (POR) according to the Bologna criteria. Methods A total of 276 infertile women undergoing IVF with POR were included in this retrospective study. They were divided into two groups with (n = 121) or without (n = 155) embryo banking at the discretion of the attending physicians. A total of 656 and 405 stimulation cycles were started in the two groups respectively during the 24 month follow‐up. Results The biochemical pregnancy, clinical pregnancy, ongoing pregnancy, and live birth rate per transfer were comparable between two groups (p > 0.05). The CLBR was significantly lower in the banking group than in the non‐banking group (31.4% (38/121) and 43.2% (67/151), p < 0.05). TTLB was significantly longer in the banking group (20.5 months vs. 16.0 months, p < 0.001). In the Kaplan–Meier analysis, the cumulative incidence of live birth was significantly lower in the banking group compared with the non‐banking group (Log rank test, chi‐square = 21.958, p < 0.001). Conclusions Embryo banking in women undergoing IVF with POR based on the Bologna criteria reduces CLBR and lengthens TTLB when compared with no embryo banking.

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