Catalysts (May 2024)
Na<sub>2</sub>SO<sub>3</sub>-Promoted Heck Coupling and Homo-Coupling of Arylhydrazines at Room Temperature
Abstract
A novel protocol facilitated by Na2SO3 that enhances the efficiency of palladium-catalyzed Heck coupling and the homo-coupling reactions of arylhydrazines. This innovative method enables the effective construction of a diverse array of cinnamate derivatives and biphenyl compounds. Notably, these transformative reactions proceed smoothly at room temperature, leveraging the activation of C-N bonds. This technique not only streamlines the synthesis process but also expands our understanding and expertise in the realm of coupling reactions.
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