Детские инфекции (Москва) (Apr 2021)

The value of interferon therapy for COVID-19 in children

  • L. N. Mazankova,
  • S. G. Gorbunov,
  • E. R. Samitova

DOI
https://doi.org/10.22627/2072-8107-2021-20-1-34-38
Journal volume & issue
Vol. 20, no. 1
pp. 34 – 38

Abstract

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The article presents a literature review, which provides data on the role of interferons in the immunopathogenesis of COVID-19 and the clinical efficacy of drugs based on recombinant interferon-alpha 2b in the treatment of children with new coronavirus infection. Shown the leading role ofinterferons as factors of the first line of defense against various viruses, including SARS-CoV-2. Numerous studies have proven the feasibility of including interferon preparations in COVID-19 therapyregimens in children, both as combinations with antiviral agents and as monotherapy.

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