Critical Care (Mar 2023)
The European guideline on management of major bleeding and coagulopathy following trauma: sixth edition
- Rolf Rossaint,
- Arash Afshari,
- Bertil Bouillon,
- Vladimir Cerny,
- Diana Cimpoesu,
- Nicola Curry,
- Jacques Duranteau,
- Daniela Filipescu,
- Oliver Grottke,
- Lars Grønlykke,
- Anatole Harrois,
- Beverley J. Hunt,
- Alexander Kaserer,
- Radko Komadina,
- Mikkel Herold Madsen,
- Marc Maegele,
- Lidia Mora,
- Louis Riddez,
- Carolina S. Romero,
- Charles-Marc Samama,
- Jean-Louis Vincent,
- Sebastian Wiberg,
- Donat R. Spahn
Affiliations
- Rolf Rossaint
- Department of Anaesthesiology, University Hospital Aachen, RWTH, Aachen University
- Arash Afshari
- Department of Paediatric and Obstetric Anaesthesia, Rigshospitalet, University of Copenhagen
- Bertil Bouillon
- Department of Trauma and Orthopaedic Surgery, Cologne-Merheim Medical Centre (CMMC), University of Witten/Herdecke
- Vladimir Cerny
- Department of Anaesthesiology, Perioperative Medicine and Intensive Care, Masaryk Hospital, J.E. Purkinje University
- Diana Cimpoesu
- Department of Emergency Medicine, Emergency County Hospital “Sf. Spiridon” Iasi, University of Medicine and Pharmacy ”Grigore T. Popa” Iasi
- Nicola Curry
- Oxford Haemophilia and Thrombosis Centre, Nuffield Orthopaedic Centre, Oxford University Hospitals NHS Trust
- Jacques Duranteau
- Department of Anesthesiology, Intensive Care and Perioperative Medicine, Assistance Publique Hôpitaux de Paris, Paris Saclay University
- Daniela Filipescu
- Department of Cardiac Anaesthesia and Intensive Care, “Prof. Dr. C. C. Iliescu” Emergency Institute of Cardiovascular Diseases, Carol Davila University of Medicine and Pharmacy
- Oliver Grottke
- Department of Anaesthesiology, University Hospital Aachen, RWTH, Aachen University
- Lars Grønlykke
- Department of Thoracic Anaesthesiology, The Heart Centre, Rigshospitalet, University of Copenhagen
- Anatole Harrois
- Department of Anesthesiology, Intensive Care and Perioperative Medicine, Assistance Publique Hôpitaux de Paris, Paris Saclay University
- Beverley J. Hunt
- Thrombosis and Haemophilia Centre, Guy’s and St Thomas’ NHS Foundation Trust
- Alexander Kaserer
- Institute of Anaesthesiology, University Hospital Zurich
- Radko Komadina
- Department of Traumatology, General and Teaching Hospital Celje, Medical Faculty, Ljubljana University
- Mikkel Herold Madsen
- Department of Paediatric and Obstetric Anaesthesia, Rigshospitalet, University of Copenhagen
- Marc Maegele
- Department of Trauma and Orthopaedic Surgery, Cologne-Merheim Medical Centre (CMMC), Institute for Research in Operative Medicine (IFOM), University of Witten/Herdecke
- Lidia Mora
- Department of Anaesthesiology, Intensive Care and Pain Clinic, Vall d’Hebron Trauma, Rehabilitation and Burns Hospital, Autonomous University of Barcelona
- Louis Riddez
- Department of Surgery and Trauma, Karolinska University Hospital
- Carolina S. Romero
- Department of Anaesthesia, Intensive Care and Pain Therapy, Consorcio Hospital General Universitario de Valencia, Universidad Europea of Valencia Methodology Research Department
- Charles-Marc Samama
- Department of Anaesthesia, Intensive Care and Perioperative Medicine, GHU AP-HP Centre - Université Paris Cité - Cochin Hospital
- Jean-Louis Vincent
- Department of Intensive Care, Erasme University Hospital, Université Libre de Bruxelles
- Sebastian Wiberg
- Department of Thoracic Anaesthesiology, The Heart Centre, Rigshospitalet, University of Copenhagen
- Donat R. Spahn
- Institute of Anaesthesiology, University Hospital Zurich
- DOI
- https://doi.org/10.1186/s13054-023-04327-7
- Journal volume & issue
-
Vol. 27,
no. 1
pp. 1 – 45
Abstract
Key messages Immediate detection and management of traumatic coagulopathy improves outcomes of severely injured patients. This guideline follows management of the severe trauma patient in chronological order, with a focus on prevention of possible exsanguination. These structured recommendations support measures that prioritise the optimisation of resources for the benefit of bleeding control based on scientific evidence. Empirical management should not be implemented unless no method of monitoring bleeding and coagulation is available. Optimal organisation of the resuscitation team for the bleeding trauma patient includes implementation of these guidelines.
Keywords
