Synthesis, antimicrobial and anticancer activities of amido sulfonamido methane linked bis heterocycles

Abstract

A new class of amido sulfonamido methane linked bis heterocycles- bis-oxazoles, thiazoles and imidazoles were prepared and screened for antimicrobial and anticancer activities. The chloro substituted amido sulfonamido bisimidazole exhibited excellent antimicrobial activity and also it was the most potent compound on lung, colon and prostate cancer cell lines.

Keywords

• Oxazoles
• Thiazoles
• Imidazoles
• Antimicrobial activity
• Anticancer activity