European Journal of Hybrid Imaging (Dec 2022)

Hyperfunctioning parathyroid gland and skeletal involvement on [18F]fluorocholine PET/CT: one look with two views

  • Carmela Nappi,
  • Leandra Piscopo,
  • Michele Klain,
  • Ciro Gabriele Mainolfi,
  • Emilia Vergara,
  • Daniela Adamo,
  • Michele Davide Mignogna,
  • Alberto Cuocolo

DOI
https://doi.org/10.1186/s41824-022-00149-y
Journal volume & issue
Vol. 6, no. 1
pp. 1 – 8

Abstract

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Abstract Hyperparathyroidism is an endocrine disorder that may be associated with other metabolic diseases. Non-invasive imaging techniques including [99mTc]Tc-sestamibi single-photon emission computed tomography (SPECT) and [18F]fluorocholine positron emission tomography (PET)/computed tomography (CT) play a key role on management of patients with hyperparathyroidism. We report for the first time a case of a patient with evidence of both hyperfunctioning parathyroid tissue and multiple lytic bone lesions on [18F]fluorocholine PET/CT imaging. The present case report highlights the potential role of whole-body [18F]fluorocholine PET/CT for the identification of both parathyroid adenoma and multiple bone lesions in a single diagnostic setting.