Forum of Clinical Oncology (Jan 2024)

Programmed Death-Ligand 1, C-reactive Protein, and Neutrophil/Lymphocyte Ratio as Lymphangiogenesis Markers of Metastasis in Penile Cancer – A Systematic Review

  • Yudiana I Wayan,
  • Marta Stacia Novia,
  • Sugianto Ronald,
  • Lestari Anak Agung Wiradewi

DOI
https://doi.org/10.2478/fco-2023-0010
Journal volume & issue
Vol. 14, no. 2
pp. 25 – 34

Abstract

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The spread of penile cancer cells through lymphatic vessels provides the potential for using compounds involved in lymphangiogenesis, such as programmed death-ligand 1 (PD-L1), C-reactive protein (CRP), neutrophil/lymphocyte ratio (NLR), and Ki-67, in predicting the development of lymphatic metastases in penile cancer.

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