Effects of a Specialized Oral Nutritional Supplement with Dietary Counseling on Nutritional Outcomes in Community-Dwelling Older Adults at Risk of Malnutrition: A Randomized Controlled Trial
Weerasak Muangpaisan,
Sanit Wichansawakun,
Dieu Thi Thu Huynh,
Somboon Intalapaporn,
Chalobol Chalermsri,
Ornicha Thititagul,
Kanokkarn Chupisanyarote,
Mallika Chuansangeam,
Arunee Laiteerapong,
Menaka Yalawar,
Chengrong Huang,
Siew Ling Tey,
Zhongyuan Liu
Affiliations
Weerasak Muangpaisan
Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
Sanit Wichansawakun
Faculty of Medicine, Thammasat University, Pathum Thani 12120, Thailand
Dieu Thi Thu Huynh
Abbott Nutrition Research and Development, Asia-Pacific Center, Singapore 138668, Singapore
Somboon Intalapaporn
Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
Chalobol Chalermsri
Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
Ornicha Thititagul
Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
Kanokkarn Chupisanyarote
Thammasat University Hospital, Thammasat University, Pathum Thani 12120, Thailand
Mallika Chuansangeam
Faculty of Medicine, Thammasat University, Pathum Thani 12120, Thailand
Arunee Laiteerapong
Abbott Nutrition Research and Development, Bangkok 10120, Thailand
Menaka Yalawar
Biostatistics and Statistical Programming, Cognizant Technologies Solution Pvt. Ltd., Bangalore 560092, India
Chengrong Huang
Abbott Nutrition Research and Development, Shanghai 200233, China
Siew Ling Tey
Abbott Nutrition Research and Development, Asia-Pacific Center, Singapore 138668, Singapore
Zhongyuan Liu
Abbott Nutrition Research and Development, Asia-Pacific Center, Singapore 138668, Singapore
This study investigated the effects of oral nutritional supplements (ONSs) along with dietary counseling (DC) in community-dwelling older adults at risk of malnutrition. In this randomized controlled trial, 196 older adults who were at risk of malnutrition, as identified by the Malnutrition Universal Screening Tool (MUST) were randomly assigned to receive ONSs twice daily with DC (intervention) or DC-only (control) for 60 days. Primary outcome was change in body weight from baseline to day 60. Nutritional status, energy, and macronutrient intakes were measured. A significant larger weight gain was observed in the intervention compared to the control from baseline to day 60 (1.50 ± 0.22 kg, p p p p = 0.0001). ONS supplementation combined with DC significantly improved body weight and nutritional outcomes in community-dwelling older adults at risk of malnutrition.
