Nature Communications (Jan 2021)

Efficient assembly of nanopore reads via highly accurate and intact error correction

  • Ying Chen,
  • Fan Nie,
  • Shang-Qian Xie,
  • Ying-Feng Zheng,
  • Qi Dai,
  • Thomas Bray,
  • Yao-Xin Wang,
  • Jian-Feng Xing,
  • Zhi-Jian Huang,
  • De-Peng Wang,
  • Li-Juan He,
  • Feng Luo,
  • Jian-Xin Wang,
  • Yi-Zhi Liu,
  • Chuan-Le Xiao

DOI
https://doi.org/10.1038/s41467-020-20236-7
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 10

Abstract

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Nanopore reads have been advantageous for de novo genome assembly; however these reads have high error rates. Here, the authors develop an error correction and de novo assembly tool, NECAT, which produces efficient, high quality assemblies of nanopore reads.