Рациональная фармакотерапия в кардиологии (Sep 2015)
FEATURES OF SEASONAL CARDIOVASCULAR MORTALITY IN WINTER IN RUSSIAN REGIONS WITH DIFFERENT CLIMATIC AND GEOGRAPHICAL CHARACTERISTICS
Abstract
Aim. To study seasonal changes in cardiovascular mortality in winter in Arkhangelsk, Ivanovo and Saratov regions – Russian regions with different climatic and geographical characteristics.Material and methods. Comparison of mortality in Arkhangelsk, Ivanovo and Saratov regions in 2007-2012 in January-March, December and April-November was performed by multivariate analysis of variance. Significance of differences was assessed by t-test of analysis of variance using programme GLM of SAS system.Results. Significantly higher cardiovascular mortality in population of Arkhangelsk (by 12.0%), Ivanovo (by 13.4%) and Saratov (by 11.5%) regions, as well as higher overall death-rate, during January-March, December, compared with April-November (p<0.0001) were found. Cardiovascular mortality decreased from 2007 to 2012 by 32.4% and by 32.9% per year and per January-March, December, respectively (p<0.0001). Higher cardiovascular mortality in the cold months of the year persisted in 2007-2012 and was higher than mortality per whole year by 8-14%. This difference in mortality did not decrease significantly (p>0.05).Conclusion. These findings point out the necessity of elaboration and implementation of the measures to prevent a winter increase in mortality, including the prevention of negative impact on the population of lowtemperature air, seasonal prophylaxis of acute respiratory viral infection, influenza and its complications, pharmacologic and non-pharmacologic prevention of cardio-vascular complications.
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