Clinicopathologic Findings in Fatal Neurotoxicity After Adoptive Immunotherapy With CD19-Directed CAR T-Cells

• Philipp Karschnia,
• Felix Strübing,
• Nico Teske,
• Viktoria Blumenberg,
• Veit L. Bücklein,
• Christian Schmidt,
• Florian Schöberl,
• Konstantinos Dimitriadis,
• Robert Forbrig,
• Hans-Joachim Stemmler,
• Joerg-Christian Tonn,
• Michael von Bergwelt-Baildon,
• Marion Subklewe,
• Louisa von Baumgarten

Affiliations

Philipp Karschnia

1 Division of Neuro-Oncology, Department of Neurosurgery, Ludwig-Maximilians-University School of Medicine, Munich, Germany

Felix Strübing

3 Center for Neuropathology and Prion Research, Ludwig-Maximilians-University School of Medicine, Munich, Germany

Nico Teske

1 Division of Neuro-Oncology, Department of Neurosurgery, Ludwig-Maximilians-University School of Medicine, Munich, Germany

Viktoria Blumenberg

2 German Cancer Consortium (DKTK), Partner Site Munich, Germany

Veit L. Bücklein

2 German Cancer Consortium (DKTK), Partner Site Munich, Germany

Christian Schmidt

2 German Cancer Consortium (DKTK), Partner Site Munich, Germany

Florian Schöberl

6 Department of Neurology, Ludwig-Maximilians-University School of Medicine, Munich, Germany

Konstantinos Dimitriadis

6 Department of Neurology, Ludwig-Maximilians-University School of Medicine, Munich, Germany

Robert Forbrig

7 Department of Neuroradiology, Ludwig-Maximilians-University School of Medicine, Munich, Germany.

Hans-Joachim Stemmler

2 German Cancer Consortium (DKTK), Partner Site Munich, Germany

Joerg-Christian Tonn

1 Division of Neuro-Oncology, Department of Neurosurgery, Ludwig-Maximilians-University School of Medicine, Munich, Germany

Michael von Bergwelt-Baildon

2 German Cancer Consortium (DKTK), Partner Site Munich, Germany

Marion Subklewe

2 German Cancer Consortium (DKTK), Partner Site Munich, Germany

Louisa von Baumgarten

1 Division of Neuro-Oncology, Department of Neurosurgery, Ludwig-Maximilians-University School of Medicine, Munich, Germany