Mediators of Inflammation (Jan 2015)

Serum Osteocalcin Is Associated with Inflammatory Factors in Metabolic Syndrome: A Population-Based Study in Chinese Males

  • Ming Liao,
  • Lirong Huang,
  • Yan Mao,
  • Yonghua Jiang,
  • Ziting Yao,
  • Xinggu Lin,
  • Zheng Lu,
  • Chunlei Wu,
  • Xue Qin,
  • Haiying Zhang,
  • Zengnan Mo

DOI
https://doi.org/10.1155/2015/683739
Journal volume & issue
Vol. 2015

Abstract

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Osteocalcin (OCN) was potentially associated with inflammatory factors, so we explored the metabolic role in this association in general population. Our findings suggest that OCN was positively associated with IgG while inversely associated with C3, both of which were probably mediated by obesity. Moreover, serum OCN was inversely associated with hsCRP in men with impaired fasting glucose, hyperglycemia, or metabolic syndrome, while its association with IgE was significantly observed in men with a normal metabolic profile.