INFLUENCE OF HYDROCORTISONE AND BETA-ADRENERGIC RECEPTOR BLOCKADE IN EFFECTOR PHASE OF THE IMMUNE RESPONSE ON PHAGOCYTIC ACTIVITY OF REGIONAL LYMPH NODE CELLS, BLOOD MONOCYTES AND PERITONEAL MACROPHAGES

Abstract

It was established that hydrocortisone reduces the phagocytic activity of regional lymph node cells and peritoneal mononuclear phagocytes, but does not affect the relative parameters of the phagocytic activity of peripheral blood monocytes in the effector phase of immune response in rats. Effects of hydrocortisone were significantly modified by the administration of beta-adrenoceptor antagonist propranolol hydrochloride.

Keywords

• beta-adrenergic receptors
• hydrocortisone
• phagocytosis
• propranolol hydrochloride
• immune response