Molecules (Jul 2018)

The Current Status of Heterogeneous Palladium Catalysed Heck and Suzuki Cross-Coupling Reactions

  • Philani P. Mpungose,
  • Zanele P. Vundla,
  • Glenn E. M. Maguire,
  • Holger B. Friedrich

DOI
https://doi.org/10.3390/molecules23071676
Journal volume & issue
Vol. 23, no. 7
p. 1676

Abstract

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In the last 30 years, C–C cross coupling reactions have become a reliable technique in organic synthesis due their versatility and efficiency. While drawbacks have been experienced on an industrial scale with the use of homogenous systems, many attempts have been made to facilitate a heterogeneous renaissance. Thus, this review gives an overview of the current status of the use of heterogeneous catalysts particularly in Suzuki and Heck reactions. Most recent developments focus on palladium immobilised or supported on various classes of supports, thus this review highlights and discuss contributions of the last decade.

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