Romanian Journal of Laboratory Medicine (Oct 2018)

Associations of vascular calcification, calcium phosphate disturbances, FGF 23 and Matrix Gla protein with mortality of hemodialysis patients: one center cohort study

  • Petrauskiene Vaida,
  • Vaiciuniene Ruta,
  • Kuzminskis Vytautas,
  • Ziginskiene Edita,
  • Grazulis Saulius,
  • Jonaitiene Egle,
  • Skrodeniene Erika,
  • Bumblyte Inga Arune

DOI
https://doi.org/10.2478/rrlm-2018-0034
Journal volume & issue
Vol. 26, no. 4
pp. 451 – 460

Abstract

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Background and objectives: Vascular calcification (VC) is one of the factors associated with mortality in hemodialysis (HD) patients. The purpose of the study was to assess associations between prevalent VC and disturbances of calcium-phosphate metabolism as well as changes in vitamin D (25(OH)D), FGF 23 and MGP levels and to evaluate the possible impact of VC and changes of these biomarkers on survival in HD patients.

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