The Invertigation Of Toxoplasma Gondii Seropositivity Among The Patients Having Undergone Coronary Angiography

Abstract

INTRODUCTION: Parasitic diseases are rare but can affect the cardiovascular system, especially in childhood. The aim of the study was to investigate the existence of a possible relationship between seroprevalence of parasites and heart diseases. METHODS: Diagnostic Coronary Angiography was performed for consecutively selected patients. Inthispatientgroup, Toxoplasma gondii IgG was examined for the presence of IgM antibodies through ELISA method. There sults were compared in terms of the values among these patients. RESULTS: A total of 183 consecutively selected patient sunderwent diagnostic coronary angiography. 110 (60%) patients were male and 83 (40%) patients were female. In our study, IgG was positive in 79 cases (71.8%) of 110 men and 66 cases (90.4%) of 73 cases were IgG positive when we examined the serum according to sex in 183 patients and IgG seropositivity against Toxoplasma gondii according to sex difference was found to be significant (p<0.05). There were 20 (10.9%) persons in the 26-45 age group, 107 (58.5%) persons in the 46-65 age group and 56 (30.6%) persons over the age of 66 years. Of the patients studied, 120 (65.5%) had normal coronary arteries or minimal coronary artery disease (coronary artery disease) (Group 1), 63 (34.5%) had severe CAD, stent and / or CABG ) were excluded (Group 2). DISCUSSION AND CONCLUSION: When the difference between IgM and IgG seropositivity in Diagnostic Angiography Group 1 and Group 2 patients was examined, no statistically significant difference was found.

Keywords

• coronary arter disease
• toxoplasma gondii
• elisa
• igm
• igg