Emerging Infectious Diseases (Mar 2016)

Preliminary Favorable Outcome for Medically and Surgically Managed Extensively Drug-Resistant Tuberculosis, France, 2009–2014

  • Benoît Henry,
  • Matthieu Revest,
  • Nathalie Dournon,
  • Loïc Epelboin,
  • Guillaume Mellon,
  • Guillaume Bellaud,
  • Pierre Mordant,
  • Damien Le Dû,
  • Nicolas Véziris,
  • Christine Bernard,
  • Sébastien Morel,
  • Stéphane Jauréguiberry,
  • Christian Michelet,
  • François Bricaire,
  • Pierre Tattevin,
  • Éric Caumes

DOI
https://doi.org/10.3201/eid2203.151130
Journal volume & issue
Vol. 22, no. 3
pp. 518 – 521

Abstract

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We report 20 cases of extensively drug-resistant tuberculosis managed in France. Treatment was individualized and included bedaquiline and linezolid for most patients and surgery in 8 patients. At last follow-up (22 months), 19 patients had achieved conversion from positive to negative on culture testing. These promising results of comprehensive management obtained in a small series deserve confirmation.

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