Technology in Cancer Research & Treatment (Jun 2022)

Application of Controlled Hypotension During Surgery for Spinal Metastasis

  • Rong-xing Ma MD,
  • Rui-qi Qiao MD,
  • Ming-you Xu MD,
  • Rui-feng Li MD,
  • Yong-cheng Hu MD, PhD

DOI
https://doi.org/10.1177/15330338221105718
Journal volume & issue
Vol. 21

Abstract

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With advances in tumor treatment, metastasis to bone is increasing, and surgery has become the only choice for most terminal patients. However, spinal surgery has a high risk and is prone to heavy bleeding. Controlled hypotension during surgery has outstanding advantages in reducing intraoperative bleeding and ensuring a clear field of vision, thus avoiding damage to important nerves and vessels. Antihypertensive drugs should be carefully selected after considering the patient's age, different diseases, etc, and a single or combined regimen can be used. Hypotension also inevitably leads to a decrease in perfusion of important organs, so the threshold of hypotension and the maintenance time of hypotension should be strictly limited, and the monitoring of important organs during the operation is particularly important. Information such as blood perfusion, blood oxygen saturation, cardiac output, and neurophysiological conduction potential changes should be obtained in a timely fashion, which will help to reduce the risk of hypotension. In short, when applying controlled hypotension, it is necessary to choose an appropriate threshold and duration, and appropriate monitoring should be conducted during the operation to ensure the safety of the patient.