Something Smells Fishy: How Lipid Mediators Impact the Maternal–Fetal Interface and Neonatal Development

Maranda Thompson; Arzu Ulu; Maheswari Mukherjee; Ana G. Yuil-Valdes; Melissa Thoene; Matthew Van Ormer; Rebecca Slotkowski; Teri Mauch; Ann Anderson-Berry; Corrine K. Hanson; Tara M. Nordgren; Sathish Kumar Natarajan

doi:10.3390/biomedicines11010171

Biomedicines (Jan 2023)

Something Smells Fishy: How Lipid Mediators Impact the Maternal–Fetal Interface and Neonatal Development

Maranda Thompson,
Arzu Ulu,
Maheswari Mukherjee,
Ana G. Yuil-Valdes,
Melissa Thoene,
Matthew Van Ormer,
Rebecca Slotkowski,
Teri Mauch,
Ann Anderson-Berry,
Corrine K. Hanson,
Tara M. Nordgren,
Sathish Kumar Natarajan

Affiliations

Maranda Thompson: Pediatrics Department, University of Nebraska Medical Center, Omaha, NE 68198, USA
Arzu Ulu: Division of Biomedical Sciences, University of California Riverside, Riverside, CA 92521, USA
Maheswari Mukherjee: Cytotechnology Education, College of Allied Health Professions, University of Nebraska Medical Center, Omaha, NE 68198, USA
Ana G. Yuil-Valdes: Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198, USA
Melissa Thoene: Pediatrics Department, University of Nebraska Medical Center, Omaha, NE 68198, USA
Matthew Van Ormer: Pediatrics Department, University of Nebraska Medical Center, Omaha, NE 68198, USA
Rebecca Slotkowski: Pediatrics Department, University of Nebraska Medical Center, Omaha, NE 68198, USA
Teri Mauch: Pediatrics Department, University of Nebraska Medical Center, Omaha, NE 68198, USA
Ann Anderson-Berry: Pediatrics Department, University of Nebraska Medical Center, Omaha, NE 68198, USA
Corrine K. Hanson: Medical Nutrition Education, College of Public Health, University of Nebraska Medical Center, Omaha, NE 68198, USA
Tara M. Nordgren: Division of Biomedical Sciences, University of California Riverside, Riverside, CA 92521, USA
Sathish Kumar Natarajan: Department of Nutrition & Health Sciences, University of Nebraska-Lincoln, Lincoln, NE 68583, USA

DOI: https://doi.org/10.3390/biomedicines11010171
Journal volume & issue: Vol. 11, no. 1
p. 171

Abstract

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Normal pregnancy relies on inflammation for implantation, placentation, and parturition, but uncontrolled inflammation can lead to poor maternal and infant outcomes. Maternal diet is one modifiable factor that can impact inflammation. Omega-3 and -6 fatty acids obtained through the diet are metabolized into bioactive compounds that effect inflammation. Recent evidence has shown that the downstream products of omega-3 and -6 fatty acids may influence physiology during pregnancy. In this review, the current knowledge relating to omega-3 and omega-6 metabolites during pregnancy will be summarized.

Published in Biomedicines

ISSN: 2227-9059 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Biology (General)
Website: http://www.mdpi.com/journal/biomedicines

About the journal

Abstract

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