ПРЕДИКТОРЫ ОТСУТСТВИЯ КОРОНАРНЫХ СТЕНОЗОВ У ПОЖИЛЫХ БОЛЬНЫХ ИШЕМИЧЕСКОЙ БОЛЕЗНЬЮ СЕРДЦА С ТИПИЧНОЙ СТАБИЛЬНОЙ СТЕНОКАРДИЕЙ

Abstract

In patients with symptoms of stable angina coronary angiography often fails to reveal significant atherosclerosis. So far as prognosis in these patients is better than in patients with significant coronary atherosclerosis (SCA) the factors associated with absence of SCA in elderly patients with stable angina have to be determined. This is a retrospective study of consecutive 16.839 patients who underwent coronary angiography. We selected 2.911 patients with stable angina and without SCA: 415 patients ≥ 65 years old and 2.496 patients younger than 65 years. Hypothyroidism as a predictor of the SCA absence in elderly patients with stable angina had the higher coefficient of equation of linear regression (OR = 1.75; 95% CI 1.13–2.71; p = 0.013). Authors hypothesized that hypothyroidism can be the cause of microvascular myocardial dysfunction which manifest clinically as stable angina in elderly patients with the absence of SCA.

Keywords

• гипофункция щитовидной железы
• пожилые больные с типичной стабильной стенокардией
• гемодинамически значимые коронарные стенозы