Data of preparation and evaluation of supramolecular hydrogel based on cellulose for sustained release of therapeutic substances with antimicrobial and wound healing properties
Adolfo Marican,
Oscar Forero-Doria,
Efrain Polo,
Jaime Gallego,
Esteban F. Durán-Lara
Affiliations
Adolfo Marican
Instituto de Química de Recursos Naturales, Universidad de Talca, Talca 3460000, Maule, Chile; Bio & NanoMaterials Lab, Drug Delivery and Controlled Release, Universidad de Talca, Talca 3460000, Maule, Chile
Oscar Forero-Doria
Instituto de Química de Recursos Naturales, Universidad de Talca, Talca 3460000, Maule, Chile
Efrain Polo
Instituto de Química de Recursos Naturales, Universidad de Talca, Talca 3460000, Maule, Chile
Jaime Gallego
Química de Recursos Energéticos y Medio Ambiente, Instituto de Química, Facultad de Ciencias Exactas y Naturales, Universidad de Antioquia UdeA, Calle 70 No. 52-21, Medellín, Colombia
Esteban F. Durán-Lara
Bio & NanoMaterials Lab, Drug Delivery and Controlled Release, Universidad de Talca, Talca 3460000, Maule, Chile; Departamento de Microbiología, Facultad de Ciencias de la Salud, Universidad de Talca, Talca 3460000, Maule, Chile; Corresponding author at: Bio & NanoMaterials Lab, Drug Delivery and Controlled Release and Departamento de Microbiología, Facultad de Ciencias de la Salud, Universidad de Talca, Talca 3460000, Maule, Chile.
The data article refers to the paper “supramolecular hydrogel based on cellulose for sustained release of therapeutic substances with antimicrobial and wound healing properties”[1]. The dataset includes the synthesis and characterization of (E)-1,3-bis(4-(allyloxy)phenyl)prop‑2-en-1-one (3) (crosslinking agent). Moreover, the multiwall carbon nanotubes (MWCNTs) synthesis and functionalization (MWCNTs-COOH) are described. The formulation obtained by adding multiwalled carbon nanotubes-COOH with the crosslinked cellulose-chalcone hydrogel is abbreviated as MWCNTsCCH, and the same formulation loaded with therapeutic substances (TS) is named MWCNTsCCH-TS. The MWCNTsCCH database such as components and their amounts, swelling degree, thermogravimetric analysis, and cytotoxicity evaluation are depicted. Finally, to elucidate the mechanism of therapeutic substances release, the obtained averages of the release profiles were fitted through mathematical models.
