Structure of the Neisseria meningitidis Type IV pilus

Subramania Kolappan; Mathieu Coureuil; Xiong Yu; Xavier Nassif; Edward H. Egelman; Lisa Craig

doi:10.1038/ncomms13015

Nature Communications (Oct 2016)

Structure of the Neisseria meningitidis Type IV pilus

Subramania Kolappan,
Mathieu Coureuil,
Xiong Yu,
Xavier Nassif,
Edward H. Egelman,
Lisa Craig

Affiliations

Subramania Kolappan: Department of Molecular Biology and Biochemistry, Simon Fraser University
Mathieu Coureuil: Institut Necker-Enfants Malades, INSERM U1151, Université Paris Descartes, 14 Rue Maria Helena Vieira Da Silva, CS 61431
Xiong Yu: Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine
Xavier Nassif: Institut Necker-Enfants Malades, INSERM U1151, Université Paris Descartes, 14 Rue Maria Helena Vieira Da Silva, CS 61431
Edward H. Egelman: Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine
Lisa Craig: Department of Molecular Biology and Biochemistry, Simon Fraser University

DOI: https://doi.org/10.1038/ncomms13015
Journal volume & issue: Vol. 7, no. 1
pp. 1 – 12

Abstract

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Type IV pili are present on a wide range of bacterial pathogens and mediate diverse functions. Here the authors report a high resolution crystal structure of the pilin subunit PilE, and a cryoEM reconstruction of the Type IV pilus filament from N. meningitidisthat offer insight into pilus assembly and functions.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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