Nature Communications (Jul 2020)
NMDAR-mediated modulation of gap junction circuit regulates olfactory learning in C. elegans
Abstract
Neural plasticity underlies learning and is regulated by modulation of gap junctions. Here, the authors show that NMDAR- and CaMKII-mediated cell autonomous downregulation of gap junction molecules in a circuit of interneurons facilitates olfactory learning affecting behavior in C. elegans.