Region-specific and state-dependent action of striatal GABAergic interneurons

Elodie Fino; Marie Vandecasteele; Sylvie Perez; Frédéric Saudou; Laurent Venance

doi:10.1038/s41467-018-05847-5

Nature Communications (Aug 2018)

Region-specific and state-dependent action of striatal GABAergic interneurons

Elodie Fino,
Marie Vandecasteele,
Sylvie Perez,
Frédéric Saudou,
Laurent Venance

Affiliations

Elodie Fino: Center for Interdisciplinary Research in Biology (CIRB), College de France, CNRS UMR7241, INSERM U1050
Marie Vandecasteele: Center for Interdisciplinary Research in Biology (CIRB), College de France, CNRS UMR7241, INSERM U1050
Sylvie Perez: Center for Interdisciplinary Research in Biology (CIRB), College de France, CNRS UMR7241, INSERM U1050
Frédéric Saudou: INSERM U1216
Laurent Venance: Center for Interdisciplinary Research in Biology (CIRB), College de France, CNRS UMR7241, INSERM U1050

DOI: https://doi.org/10.1038/s41467-018-05847-5
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 17

Abstract

Read online

Striatal GABAergic interneurons regulate the influence of cortical inputs on striatal projection neurons through feedforward inhibition. Here, the authors report that this inhibition is mediated mainly by PV interneurons in the dorsolateral striatum and SOM interneurons in the dorsomedial striatum.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

About the journal