Comparative efficacy of autologous alveolar bone grafting with autologous platelet-rich plasma and without platelet-rich plasma in cleft alveolus patients

Abstract

Aim: The aim of this longitudinal study was to evaluate the efficacy of alveolar bone grafting with autologous platelet-rich plasma (PRP) over cancellous bone grafting alone in cleft alveolus patients. Materials and Methods: A total of 30 patients were evaluated, out of which 15 patients were subjected to alveolar bone grafting with cancellous bone and 15 patients underwent alveolar bone grafting with autologous PRP along with cancellous bone graft. Autologous PRP was extracted using a plasma centrifuge machine. Chi-square test was used for statistical analysis, which revealed statistically significant (P < 0.05) in the study group and control group. Results: Radiographic evaluation was done on the amount of graft resorption at the end of 6 months postoperatively. Success of the graft was assessed with the help of Bergland scoring criteria. Conclusion: Results obtained from our study suggested that resorption of bone graft was comparatively less in the study group as compared to control group.

Keywords

• alveolar bone grafting
• cleft alveolus
• platelet-rich plasma