Future Science OA (Oct 2021)
The viral capsid as novel nanomaterials for drug delivery
- Alaa AA Aljabali,
- Sk Sarif Hassan,
- Ritesh M Pabari,
- Seyed H Shahcheraghi,
- Vijay Mishra,
- Nitin B Charbe,
- Dinesh K Chellappan,
- Harish Dureja,
- Gaurav Gupta,
- Abdulmajeed G Almutary,
- Abdullah M Alnuqaydan,
- Suresh K Verma,
- Pritam K Panda,
- Yogendra Kumar Mishra,
- Ángel Serrano-Aroca,
- Kamal Dua,
- Vladimir N Uversky,
- Elrashdy M Redwan,
- Bojlul Bahar,
- Amit Bhatia,
- Poonam Negi,
- Rohit Goyal,
- Paul McCarron,
- Hamid A Bakshi,
- Murtaza M Tambuwala
Affiliations
- Alaa AA Aljabali
- 1Faculty of Pharmacy, Department of Pharmaceutics & Pharmaceutical Technology, Yarmouk University, Irbid, 21163, Jordan
- Sk Sarif Hassan
- 2Department of Mathematics, Pingla Thana Mahavidyalaya, Paschim Medinipur, India
- Ritesh M Pabari
- 3School of Pharmacy, Royal College of Surgeons in Ireland, Dublin, Ireland
- Seyed H Shahcheraghi
- 4Infectious Diseases Research Center, Shahid Sadoughi Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
- Vijay Mishra
- 5School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab, 144411, India
- Nitin B Charbe
- 6Department of Pharmaceutical Sciences, Rangel College of Pharmacy, Texas A&M University, Kingsville, TX 78363, USA
- Dinesh K Chellappan
- 7Department of Life Sciences, School of Pharmacy, International Medical University, Bukit Jalil, Kuala Lumpur, 57000, Malaysia
- Harish Dureja
- 8Department of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak, 124001, India
- Gaurav Gupta
- 9School of Pharmacy, Suresh Gyan Vihar University, Mahal Road, Jagatpura, Jaipur, 302017, India
- Abdulmajeed G Almutary
- 10Department of Medical Biotechnology, College of Applied Medical Sciences, Qassim University, Saudi Arabia
- Abdullah M Alnuqaydan
- 10Department of Medical Biotechnology, College of Applied Medical Sciences, Qassim University, Saudi Arabia
- Suresh K Verma
- 11Condensed Matter Theory Group, Materials Theory Division, Department of Physics & Astronomy, Uppsala University, Uppsala, 75120, Sweden
- Pritam K Panda
- 11Condensed Matter Theory Group, Materials Theory Division, Department of Physics & Astronomy, Uppsala University, Uppsala, 75120, Sweden
- Yogendra Kumar Mishra
- 12University of Southern Denmark, Mads Clausen Institute, NanoSYD, Alsion 2, Sønderborg 6400, Denmark
- Ángel Serrano-Aroca
- 13Biomaterials & Bioengineering Lab, Centro de Investigación Traslacional San Alberto Magno, Universidad Católica de Valencia San Vicente Mártir, Valencia, 46001, Spain
- Kamal Dua
- 14Discipline of Pharmacy, Graduate School of Health, University of Technology, Sydney, Australia
- Vladimir N Uversky
- 15Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL 33612, USA
- Elrashdy M Redwan
- 16King Abdulazizi University, Faculty of Science, Department of Biological Science, Saudi Arabia
- Bojlul Bahar
- 17International Institute of Nutritional Sciences & Food Safety Studies, School of Sport & Health Sciences, University of Central Lancashire, Preston, Lancashire, PR1 2HE, UK
- Amit Bhatia
- 18Maharaja Ranjit Singh Punjab Technical University Dabwali Road, Bathinda, Punjab, 151001, India
- Poonam Negi
- 19School of Pharmaceutical Sciences, Shoolini University of Biotechnology & Management Sciences, Solan, 173229, India
- Rohit Goyal
- 19School of Pharmaceutical Sciences, Shoolini University of Biotechnology & Management Sciences, Solan, 173229, India
- Paul McCarron
- 20School of Pharmacy & Pharmaceutical Science, Ulster University, Coleraine, County Londonderry, Northern Ireland, BT52 1SA, UK
- Hamid A Bakshi
- 20School of Pharmacy & Pharmaceutical Science, Ulster University, Coleraine, County Londonderry, Northern Ireland, BT52 1SA, UK
- Murtaza M Tambuwala
- 20School of Pharmacy & Pharmaceutical Science, Ulster University, Coleraine, County Londonderry, Northern Ireland, BT52 1SA, UK
- DOI
- https://doi.org/10.2144/fsoa-2021-0031
- Journal volume & issue
-
Vol. 7,
no. 9
Abstract
The purpose of this review is to highlight recent scientific developments and provide an overview of virus self-assembly and viral particle dynamics. Viruses are organized supramolecular structures with distinct yet related features and functions. Plant viruses are extensively used in biotechnology, and virus-like particulate matter is generated by genetic modification. Both provide a material-based means for selective distribution and delivery of drug molecules. Through surface engineering of their capsids, virus-derived nanomaterials facilitate various potential applications for selective drug delivery. Viruses have significant implications in chemotherapy, gene transfer, vaccine production, immunotherapy and molecular imaging.
Keywords
