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Military Medical Research
(Dec 2023)
BET inhibitors potentiate melanoma ferroptosis and immunotherapy through AKR1C2 inhibition
Yu Meng,
Hui-Yan Sun,
Yi He,
Qian Zhou,
Yi-Huang Liu,
Hui Su,
Ming-Zhu Yin,
Fu-Rong Zeng,
Xiang Chen,
Guang-Tong Deng
Affiliations
Yu Meng
Department of Dermatology, Xiangya Hospital, Central South University
Hui-Yan Sun
Department of Dermatology, Xiangya Hospital, Central South University
Yi He
Department of Dermatology, Xiangya Hospital, Central South University
Qian Zhou
Department of Dermatology, Xiangya Hospital, Central South University
Yi-Huang Liu
Department of Dermatology, Xiangya Hospital, Central South University
Hui Su
Department of Dermatology, Xiangya Hospital, Central South University
Ming-Zhu Yin
Department of Dermatology, Xiangya Hospital, Central South University
Fu-Rong Zeng
Department of Oncology, Xiangya Hospital, Central South University
Xiang Chen
Department of Dermatology, Xiangya Hospital, Central South University
Guang-Tong Deng
Department of Dermatology, Xiangya Hospital, Central South University
DOI
https://doi.org/10.1186/s40779-023-00497-1
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 5
Abstract
Read online
No abstracts available.
Keywords
Melanoma
Bromodomain and extra terminal domain (BET) inhibitor
Ferroptosis
Cell death
AKR1C2
Immunotherapy
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