Cell Reports: Methods (Jul 2024)

“Forcing” new interpretations of molecular tension sensor studies

  • Matthew R. Pawlak,
  • Adam T. Smiley,
  • Wendy R. Gordon

Journal volume & issue
Vol. 4, no. 7
p. 100821

Abstract

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Molecular tension sensors are central tools for mechanobiology studies but have limitations in interpretation. Reporting in Cell Reports Methods, Shoyer et al. discover that fluorescent protein photoswitching in concert with sensor extension may expand the use and interpretation of common force-sensing tools.

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