Serine Metabolism Tunes Immune Responses To Promote
<i>Oreochromis niloticus</i>
Survival upon
<i>Edwardsiella tarda</i>
Infection
Dai-Xiao Yang,
Man-Jun Yang,
Yue Yin,
Tian-Shun Kou,
Liao-Tian Peng,
Zhuang-Gui Chen,
Jun Zheng,
Bo Peng
Affiliations
Dai-Xiao Yang
Center for Proteomics and Metabolomics, State Key Laboratory of Biocontrol, Guangdong Key Laboratory of Pharmaceutical Functional Genes, School of Life Sciences, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Sun Yat-sen University, Guangzhou, People’s Republic of China
Man-Jun Yang
Center for Proteomics and Metabolomics, State Key Laboratory of Biocontrol, Guangdong Key Laboratory of Pharmaceutical Functional Genes, School of Life Sciences, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Sun Yat-sen University, Guangzhou, People’s Republic of China
Yue Yin
Center for Proteomics and Metabolomics, State Key Laboratory of Biocontrol, Guangdong Key Laboratory of Pharmaceutical Functional Genes, School of Life Sciences, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Sun Yat-sen University, Guangzhou, People’s Republic of China
Tian-Shun Kou
Center for Proteomics and Metabolomics, State Key Laboratory of Biocontrol, Guangdong Key Laboratory of Pharmaceutical Functional Genes, School of Life Sciences, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Sun Yat-sen University, Guangzhou, People’s Republic of China
Liao-Tian Peng
Center for Proteomics and Metabolomics, State Key Laboratory of Biocontrol, Guangdong Key Laboratory of Pharmaceutical Functional Genes, School of Life Sciences, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Sun Yat-sen University, Guangzhou, People’s Republic of China
Zhuang-Gui Chen
Department of Pediatrics, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
Jun Zheng
Faculty of Health Sciences, University of Macau, Macau SAR, China
Center for Proteomics and Metabolomics, State Key Laboratory of Biocontrol, Guangdong Key Laboratory of Pharmaceutical Functional Genes, School of Life Sciences, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Sun Yat-sen University, Guangzhou, People’s Republic of China
Bacterial virulence factors are not the only factors responsible for host death. Overactive immune responses, such as cytokine storm, contribute to tissue injury that results in organ failure and ultimately the death of the host.
