mSystems (Aug 2021)

Serine Metabolism Tunes Immune Responses To Promote <i>Oreochromis niloticus</i> Survival upon <i>Edwardsiella tarda</i> Infection

  • Dai-Xiao Yang,
  • Man-Jun Yang,
  • Yue Yin,
  • Tian-Shun Kou,
  • Liao-Tian Peng,
  • Zhuang-Gui Chen,
  • Jun Zheng,
  • Bo Peng

DOI
https://doi.org/10.1128/mSystems.00426-21
Journal volume & issue
Vol. 6, no. 4

Abstract

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Bacterial virulence factors are not the only factors responsible for host death. Overactive immune responses, such as cytokine storm, contribute to tissue injury that results in organ failure and ultimately the death of the host.