mBio
(Feb 2021)
Zn
<sup>2+</sup>
Intoxication of Mycobacterium marinum during Dictyostelium discoideum Infection Is Counteracted by Induction of the Pathogen Zn
<sup>2+</sup>
Exporter CtpC
Nabil Hanna,
Hendrik Koliwer-Brandl,
Louise H. Lefrançois,
Vera Kalinina,
Elena Cardenal-Muñoz,
Joddy Appiah,
Florence Leuba,
Aurélie Gueho,
Hubert Hilbi,
Thierry Soldati,
Caroline Barisch
Affiliations
Nabil Hanna
ORCiD Department of Biochemistry, Faculty of Science, University of Geneva, Geneva, Switzerland
Hendrik Koliwer-Brandl
ORCiD Institute of Medical Microbiology, University of Zurich, Zurich, Switzerland
Louise H. Lefrançois
ORCiD Department of Biochemistry, Faculty of Science, University of Geneva, Geneva, Switzerland
Vera Kalinina
ORCiD Department of Biochemistry, Faculty of Science, University of Geneva, Geneva, Switzerland
Elena Cardenal-Muñoz
ORCiD Department of Biochemistry, Faculty of Science, University of Geneva, Geneva, Switzerland
Joddy Appiah
ORCiD Department of Biochemistry, Faculty of Science, University of Geneva, Geneva, Switzerland
Florence Leuba
ORCiD Department of Biochemistry, Faculty of Science, University of Geneva, Geneva, Switzerland
Aurélie Gueho
ORCiD Department of Biochemistry, Faculty of Science, University of Geneva, Geneva, Switzerland
Hubert Hilbi
ORCiD Institute of Medical Microbiology, University of Zurich, Zurich, Switzerland
Thierry Soldati
ORCiD Department of Biochemistry, Faculty of Science, University of Geneva, Geneva, Switzerland
Caroline Barisch
ORCiD Department of Biochemistry, Faculty of Science, University of Geneva, Geneva, Switzerland
DOI
https://doi.org/10.1128/mBio.01313-20
Journal volume & issue
Vol. 12,
no. 1
Abstract
Read online
Microelements are essential for the function of the innate immune system. A deficiency in zinc or copper results in an increased susceptibility to bacterial infections.
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