Nature Communications (Apr 2016)

Catalytic N-radical cascade reaction of hydrazones by oxidative deprotonation electron transfer and TEMPO mediation

  • Xiao-Qiang Hu,
  • Xiaotian Qi,
  • Jia-Rong Chen,
  • Quan-Qing Zhao,
  • Qiang Wei,
  • Yu Lan,
  • Wen-Jing Xiao

DOI
https://doi.org/10.1038/ncomms11188
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 12

Abstract

Read online

The use of N-centred radicals is limited by the difficulties in their preparation. Here, the authors report a photoredox method for the formation of N-centred radicals on hydrazones and their use for the synthesis of heterocyclic compounds through a radical cascade reaction.