High-resolution dataset of manual claustrum segmentation

Abstract

The claustrum has a unique thin sheet-like structure that makes it hard to identify in typical anatomical MRI scans. Attempts have been made to identify the claustrum in anatomical images with either automatic segmentation techniques or using atlas-based approaches. However, the resulting labels fail to include the ventral claustrum portion, which consists of fragmented grey matter referred to as “puddles”. The current dataset is a high-resolution label of the whole claustrum manually defined using an ultra-high resolution postmortem MRI image of one individual. Manual labelling was performed by four independent research trainees. Two trainees labelled the left claustrum and another two trainees labelled the right claustrum. For every hemisphere we created a union of the two labels and assessed the label correspondence using dice coefficients. We provide size measurements of the labels in MNI space by calculating the oriented bounding box size. These data are the first manual claustrum segmentation labels that include both the dorsal and ventral claustrum regions at such a high resolution in standard space. The label can be used to approximate the claustrum location in typical in vivo MRI scans of healthy individuals.

Keywords

• Claustrum
• Segmentation
• MRI
• MNI space
• Label
• Manual