Mean Platelet Volume to Lymphocyte Ratio: A Novel Marker For Idiopathic Sudden Sensorineural Hearing Loss

Abstract

Aim:To investigate the value of mean platelet volume (MPV) to lymphocyte ratio (MPVLR), a novel marker, in determining the prognosis of sudden sensorineural hearing loss (SSNHL).Materials and Methods:This retrospective cross-sectional study study included the patient group consisting of 65 SSNHL and the control group consisting of 50 healthy individuals. 65 patients with SSNHL were divided into two subgroups as 44 recovered patients and 21 unrecovered patients. The SSHNL patients and the control group, and the recovered SSNHL patients and the unrecovered SSNHL patients were compared statistically in terms of MPV, lymphocyte count and MPVLR.Results:The mean MPV value was 9.28 ± 0.99 fL in the patients and 9.25 ±0.82 fL in the control group, and the difference was not statistically significant (p = 0,851). The mean lymphocyte count was 1.90 ± 1.02 in the study group and 2.55± 0.78 in the control group, and the difference was statistically significant (p <0.001). The mean MPVLR value was 6.44 ± 4.14 in the study group and 4.03 ± 1.62 in the control group and the difference was statistically significant (p<0,05).Conclusion:MPVLR is an easily accessible marker and levels are increased by severity of the disease. The lymphocyte count is also declined according to the severity of the disease. These results showed that MPVLR and lymphocyte count can help to predict the SSNHL prognosis. With future studies, the value of MPVLR in the prognosis of SSNHL may be better understood.

Keywords

• mean platelet volume
• mean platelet volume to lymphocyte ratio
• sudden sensorineural hearing loss