Dimethyl 2-[24-acetyl-28-oxo-8,11,14-trioxa-24,27-diazapentacyclo[,26.02,7.015,20]octacosa-2,4,6,15(20),16,18-hexaen-27-yl]but-2-enedioate

Acta Crystallographica Section E. 2012;68(8):o2431-o2432 DOI 10.1107/S1600536812030644


Journal Homepage

Journal Title: Acta Crystallographica Section E

ISSN: 1600-5368 (Print)

Publisher: International Union of Crystallography

LCC Subject Category: Science: Chemistry

Country of publisher: United Kingdom

Language of fulltext: English

Full-text formats available: PDF, HTML



Truong Hong Hieu
Le Tuan Anh
Anatoly T. Soldatenkov
Nadezhda M. Kolyadina
Victor N. Khrustalev


Blind peer review

Editorial Board

Instructions for authors

Time From Submission to Publication: 3 weeks


Abstract | Full Text

The title compound, C31H34N2O9, is a product of the Michael addition of the cyclic secondary amine subunit of the (bispidino)aza-14-crown-4 ether to dimethyl acetylenedicarboxylate. The molecule comprises a tricyclic system containing the aza-14-crown-3 ether macrocycle and two six-membered piperidinone rings. The aza-14-crown-3-ether ring adopts a bowl conformation with a dihedral angle between the planes of the fused benzene rings of 51.14 (5)°. The central piperidone ring has a boat conformation, whereas the terminal piperidone ring adopts a chair conformation. The dimethyl ethylenedicarboxylate fragment has a cis configuration with a dihedral angle of 56.56 (7)° between the two carboxylate groups. The crystal packing is stabilized by weak C—H...O hydrogen bonds.