Approaches to interpret the outcomes of a network meta-analysis on comparative efficacy of different targeted therapies plus fulvestrant for advanced breast cancer following progression on prior endocrine therapy

Abstract

Rama Jayaraj,1 Chellan Kumarasamy,2 Shanthi Sabarimurugan,3 Suja Samiappan41College of Health and Human Sciences, Charles Darwin University, Casuarina, Northern Territory 0909, Australia; 2University of Adelaide, Adelaide, South Australia 5005, Australia; 3School of Biosciences and Technology, Vellore Institute of Technology (VIT), Vellore, Tamil Nadu, India; 4Department of Biochemistry, Bharathiar University, Coimbatore, Tamil Nadu, IndiaZhang and colleagues have conducted a network meta-analysis regarding fulvestrant combined targeted therapies for breast cancer, which has been published in the Cancer Management and Research journal.1 The study itself is interesting in its approach.View the original paper by Zhang and colleagues.

Keywords

• Advanced breast cancer Targeted therapies plus fulvestrant Endocrine therapy Network Meta-Analysis Treatment efficacy Clinical interpretation