P1563: INTRACELLULAR IRON OVERLOAD IMPAIRS HSC FUNCTION BY AFFECTING MITOCHONDRIAL FITNESS IN ΒETA-THALASSEMIA

• S. Sighinolfi,
• A. Aprile,
• L. Cassina,
• M. Panzeri,
• S. Beretta,
• M. Storto,
• A. Boletta,
• I. Merelli,
• G. Ferrari

Affiliations

S. Sighinolfi

1 San Raffaele-Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy

A. Aprile

1 San Raffaele-Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy

L. Cassina

3 Division of Genetics and Cell Biology, Dibit, San Raffaele Scientific Institute, Milan, Italy

M. Panzeri

4 Advanced Light and Electron Microscopy BioImaging Center (ALEMBIC), San Raffaele, Milan, Italy

S. Beretta

1 San Raffaele-Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy

M. Storto

1 San Raffaele-Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy

A. Boletta

3 Division of Genetics and Cell Biology, Dibit, San Raffaele Scientific Institute, Milan, Italy

I. Merelli

1 San Raffaele-Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy

G. Ferrari

1 San Raffaele-Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy