The role of cytokines in the pathogenesis of autoimmune diabetes, immune intervention issues

Abstract

The review devotes to studying the role of cytokines in development of autoimmune diabetes mellitus, latent autoimmune diabetes in adults included. Therapeutic approaches to prevent the loss of endogenous insulin secretion are discussed. There is review of clinical trials of immunosuppressive agents and modulators of immune tolerance in autoimmune diabetes mellitus.

Keywords

• аутоиммунный сахарный диабет
• сахарный диабет типа 1а
• латентный аутоиммунный диабет взрослых
• цитокины
• иммунологическая толерантность
• иммуноинтервенция