Fullerene C60 impact on changes of contraction speed of ischemicaly damaged rat soleus muscle

Abstract

The effect of water-soluble C 60 fullerene (C 60 FAS) at a dose of 1 mg/kg on ischemic damagd muscles (muscle soleus) of rat was studied. The therapeutic effect of C 60 FAS was analyzed under intravenous and intramuscular injection. An evident C 60 FAS protective effect on the dynamics of ischemic damage muscles contraction was revealed. In particular, it was found that in most cases the protective effect of С 60 FAS with intramuscular administration at 15-17% is more effective than intravenous administration of this drug. This clearly indicates that C 60 FAS can be considered as a promising therapeutic agent for the prevention and correction of contractile activity of ischemic damage muscles.

Keywords

• muscle, ischemia, contraction dynamics, power answer, fullerene C60.