Frontiers in Oncology (Jan 2022)
Endoscopic Endonasal Intraconal Approach for Orbital Tumor Resection: Case Series and Systematic Review
- Xin Zhang,
- Xin Zhang,
- Xin Zhang,
- Xin Zhang,
- Xin Zhang,
- Wei Hua,
- Wei Hua,
- Wei Hua,
- Wei Hua,
- Wei Hua,
- Wei Hua,
- Kai Quan,
- Kai Quan,
- Kai Quan,
- Kai Quan,
- Kai Quan,
- Guo Yu,
- Guo Yu,
- Guo Yu,
- Guo Yu,
- Guo Yu,
- Zunguo Du,
- Zixiao Yang,
- Zixiao Yang,
- Zixiao Yang,
- Zixiao Yang,
- Zixiao Yang,
- Xiaowen Wang,
- Xiaowen Wang,
- Xiaowen Wang,
- Xiaowen Wang,
- Xiaowen Wang,
- Jianping Song,
- Jianping Song,
- Jianping Song,
- Jianping Song,
- Jianping Song,
- Liang Chen,
- Liang Chen,
- Liang Chen,
- Liang Chen,
- Liang Chen,
- Wei Zhu,
- Wei Zhu,
- Wei Zhu,
- Wei Zhu,
- Wei Zhu
Affiliations
- Xin Zhang
- Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
- Xin Zhang
- National Center for Neurological Disorders, Shanghai, China
- Xin Zhang
- Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Shanghai, China
- Xin Zhang
- Neurosurgical Institute of Fudan University, Shanghai, China
- Xin Zhang
- Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China
- Wei Hua
- Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
- Wei Hua
- National Center for Neurological Disorders, Shanghai, China
- Wei Hua
- Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Shanghai, China
- Wei Hua
- Neurosurgical Institute of Fudan University, Shanghai, China
- Wei Hua
- Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China
- Wei Hua
- Research Unit of New Technologies of Micro-Endoscopy Combination in Skull Base Surgery (2018RU008), Chinese Academy of Medical Science, Shanghai, China
- Kai Quan
- Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
- Kai Quan
- National Center for Neurological Disorders, Shanghai, China
- Kai Quan
- Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Shanghai, China
- Kai Quan
- Neurosurgical Institute of Fudan University, Shanghai, China
- Kai Quan
- Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China
- Guo Yu
- Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
- Guo Yu
- National Center for Neurological Disorders, Shanghai, China
- Guo Yu
- Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Shanghai, China
- Guo Yu
- Neurosurgical Institute of Fudan University, Shanghai, China
- Guo Yu
- Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China
- Zunguo Du
- Department of Pathology, Huashan Hospital, Fudan University, Shanghai, China
- Zixiao Yang
- Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
- Zixiao Yang
- National Center for Neurological Disorders, Shanghai, China
- Zixiao Yang
- Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Shanghai, China
- Zixiao Yang
- Neurosurgical Institute of Fudan University, Shanghai, China
- Zixiao Yang
- Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China
- Xiaowen Wang
- Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
- Xiaowen Wang
- National Center for Neurological Disorders, Shanghai, China
- Xiaowen Wang
- Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Shanghai, China
- Xiaowen Wang
- Neurosurgical Institute of Fudan University, Shanghai, China
- Xiaowen Wang
- Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China
- Jianping Song
- Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
- Jianping Song
- National Center for Neurological Disorders, Shanghai, China
- Jianping Song
- Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Shanghai, China
- Jianping Song
- Neurosurgical Institute of Fudan University, Shanghai, China
- Jianping Song
- Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China
- Liang Chen
- Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
- Liang Chen
- National Center for Neurological Disorders, Shanghai, China
- Liang Chen
- Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Shanghai, China
- Liang Chen
- Neurosurgical Institute of Fudan University, Shanghai, China
- Liang Chen
- Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China
- Wei Zhu
- Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
- Wei Zhu
- National Center for Neurological Disorders, Shanghai, China
- Wei Zhu
- Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Shanghai, China
- Wei Zhu
- Neurosurgical Institute of Fudan University, Shanghai, China
- Wei Zhu
- Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China
- DOI
- https://doi.org/10.3389/fonc.2021.780551
- Journal volume & issue
-
Vol. 11
Abstract
Intraorbital tumor could be approached by numerous surgical methods. The neuroendoscopic endonasal approach could provide a feasible corridor for indicated tumors. Herein we present a series of 6 consecutive intraorbital tumors from April 2018 to October 2020, which received endonasal endoscopic resection. Cadaveric dissection was performed for the intraconal approach, and the literature was also reviewed. Five tumors were located intraconally, while one extraconally. The pathology revealed 1 angioleiomyoma, 1 cavernous hemangioma, 1 pilocytic astrocytoma, 1 meningioma, and 2 schwannomas. Five of the six achieved gross total resection, including 3 tumors with lateral extension beyond the optic nerve. Preoperative visual deterioration was observed in 4 of the 6 patients, and all got improvement postoperatively. Transient oculomotor nerve palsy was presented in one patient postoperatively. No cerebrospinal fluid leakage, enophthalmos, or strabismus was observed. The median follow-up time is 27 months (11~41 months). At the 6-month follow-up, the visual acuity remained unchanged compared with that at discharge. Proptosis was resolved in 2 of the 3 patients; diplopia was improved in one patient. In conclusion, endoscopic endonasal intraconal approach could be suitable for selected pathological conditions, and for both medial or beyond medial extraconal and intraconal orbital tumors.
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