Inhibition of hypoxia-induced Mucin 1 alters proteomic composition of human osteoblast-produced extracellular matrix, leading to reduced osteogenic and angiogenic potential

• Pavitra Kumar,
• Shuang Zhang,
• Marijke Koedam,
• Jeroen Demmers,
• Suvro Chatterjee,
• Johannes van Leeuwen,
• Bram van der Eerden

Affiliations

Pavitra Kumar

University of Berne, Clinical Research, Berne, Switzerland; Erasmus MC, Internal Medicine, Rotterdam, Netherlands

Shuang Zhang

Erasmus MC, Internal Medicine, Rotterdam, Netherlands

Marijke Koedam

Erasmus MC, Internal Medicine, Rotterdam, Netherlands

Jeroen Demmers

Erasmus MC, Proteomics, Rotterdam, Netherlands

Suvro Chatterjee

Anna University, Biotechnology, Chennai, India

Johannes van Leeuwen

Erasmus MC, Internal Medicine, Rotterdam, Netherlands

Bram van der Eerden

Erasmus MC, Internal Medicine, Rotterdam, Netherlands; Corresponding author.