Nature Communications (Sep 2016)
Systematic functional analysis of kinases in the fungal pathogen Cryptococcus neoformans
- Kyung-Tae Lee,
- Yee-Seul So,
- Dong-Hoon Yang,
- Kwang-Woo Jung,
- Jaeyoung Choi,
- Dong-Gi Lee,
- Hyojeong Kwon,
- Juyeong Jang,
- Li Li Wang,
- Soohyun Cha,
- Gena Lee Meyers,
- Eunji Jeong,
- Jae-Hyung Jin,
- Yeonseon Lee,
- Joohyeon Hong,
- Soohyun Bang,
- Je-Hyun Ji,
- Goun Park,
- Hyo-Jeong Byun,
- Sung Woo Park,
- Young-Min Park,
- Gloria Adedoyin,
- Taeyup Kim,
- Anna F. Averette,
- Jong-Soon Choi,
- Joseph Heitman,
- Eunji Cheong,
- Yong-Hwan Lee,
- Yong-Sun Bahn
Affiliations
- Kyung-Tae Lee
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Yee-Seul So
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Dong-Hoon Yang
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Kwang-Woo Jung
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Jaeyoung Choi
- Department of Agricultural Biotechnology, Seoul National University
- Dong-Gi Lee
- Biological Disaster Analysis Group, Korea Basic Science Institute
- Hyojeong Kwon
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Juyeong Jang
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Li Li Wang
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Soohyun Cha
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Gena Lee Meyers
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Eunji Jeong
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Jae-Hyung Jin
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Yeonseon Lee
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Joohyeon Hong
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Soohyun Bang
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Je-Hyun Ji
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Goun Park
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Hyo-Jeong Byun
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Sung Woo Park
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Young-Min Park
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Gloria Adedoyin
- Departments of Molecular Genetics and Microbiology, Medicine, and Pharmacology and Cancer Biology, Duke University Medical Center
- Taeyup Kim
- Departments of Molecular Genetics and Microbiology, Medicine, and Pharmacology and Cancer Biology, Duke University Medical Center
- Anna F. Averette
- Departments of Molecular Genetics and Microbiology, Medicine, and Pharmacology and Cancer Biology, Duke University Medical Center
- Jong-Soon Choi
- Biological Disaster Analysis Group, Korea Basic Science Institute
- Joseph Heitman
- Departments of Molecular Genetics and Microbiology, Medicine, and Pharmacology and Cancer Biology, Duke University Medical Center
- Eunji Cheong
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- Yong-Hwan Lee
- Department of Agricultural Biotechnology, Seoul National University
- Yong-Sun Bahn
- Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University
- DOI
- https://doi.org/10.1038/ncomms12766
- Journal volume & issue
-
Vol. 7,
no. 1
pp. 1 – 16
Abstract
Cryptococcus neoformans is the leading cause of death by fungal meningoencephalitis. Here, the authors study the roles played by 129 putative kinases in the growth and virulence of C. neoformans, identifying potential targets for development of anticryptococcal drugs.
