Infection and Drug Resistance (Nov 2020)
Prevalence and Risk Factors of Asymptomatic Plasmodium Infection in Gondar Zuria District, Northwest Ethiopia
Abstract
Awoke Minwuyelet,1 Tegegne Eshetu,1 Dagnaneh Milikit,1 Yibeltal Aschale2 1Department of Medical Parasitology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia; 2Department of Medical Laboratory Sciences, College of Health Sciences, Debre Markos University, Debre Markos, EthiopiaCorrespondence: Yibeltal AschaleCollege of Health Sciences, Debre Markos University, P.O. Box 269, Debre Markos, EthiopiaTel +251922444340Email [email protected]: Malaria is one of the major public health problems worldwide. In Ethiopia, an increase in malaria incidence may be attributed to the presence of community-wide asymptomatic Plasmodium infection. This study aims to assess asymptomatic Plasmodium infection and associated factors in Gondar Zuria district, Northwest Ethiopia.Methods: A community-based cross-sectional study was conducted in Gondar Zuria district from May to June 2019. Angacha and Hamsafeg villages were randomly selected from Tachtseda and Hamsafeg kebeles, respectively. Fifty-three (53) households were selected using systematic random sampling to recruit a total of 251 study participants. Sociodemographic data were collected using structured questionnaires. Thin and thick blood films were prepared and examined for evidence of parasites. Data were entered and analyzed using SPSS version 23. The association between dependent (asymptomatic Plasmodium infection) and independent (sex, age group, family size and previous history of malaria) variables was explored using bivariate and multivariate logistic regression. Statistically significant association was declared at a P-value of < 0.05.Results: A total of 251 individuals were tested, of whom 53.4% were females and 33.5% were above the age of 30 years. The prevalence of asymptomatic Plasmodium infection was 12%. The highest prevalence of malaria was observed in females (6.4%) and among the age group 15– 29 years (4.4%). The majority (70%) of study participants had < 500 parasites/μL of blood. A high parasitemia level (ie ≥ 1000 parasites/μL of blood) was observed in the age group 15– 29 years. Age group, bed net usage and previous history of malaria were significantly associated with asymptomatic Plasmodium infection (P< 0.05).Conclusion: Asymptomatic Plasmodium infection remains an important public health problem in the study area. Further studies using more sensitive diagnostic methods are required to scale up the eradication and control program of malaria.Keywords: asymptomatic malaria, Plasmodium infection, Gondar Zuria, Ethiopia
