1294 External validation of machine learning models to predict efficacy and toxicity of immune checkpoint inhibitors using real-world pan cancer cohorts

• Jens Siveke,
• Alexander Roesch,
• Viktor Grünwald,
• Zoltan Kiss,
• Jan Wolber,
• Martin Schuler,
• Julius Keyl,
• Levente Lippenszky,
• Pablo Napan-Molina,
• Eszter Csernai,
• Travis Osterman,
• Balazs Laczi,
• Alexander Brehmer,
• Moon Kim,
• Moritz Meyer,
• Stefan Kasper,
• Jens Kleesiek

Affiliations

Jens Siveke

6Bridge Institute of Experimental Tumor Therapy (BIT), West German Cancer Center, University Hospital Essen (AöR), Essen, Nordrhein-Westfalen, Germany

Alexander Roesch

Department of Dermatology, Venereology and Allergology, University Hospital Essen, Essen, Germany and German Cancer Consortium (DKTK) partner site Essen/Düsseldorf, Essen, Germany

Viktor Grünwald

Department of Medical Oncology, West German Cancer Center, University Hospital Essen, Essen, Germany

Zoltan Kiss

1Science and Technology Organization – Artificial Intelligence and Machine Learning, GE HealthCare, Budapest, Budapest, Hungary

Jan Wolber

GE Healthcare, Amersham, UK

Martin Schuler

9University Hospital Essen, Essen, Germany

Julius Keyl

4Institute of Pathology, University Hospital Essen (AöR), University of Duisburg-Essen, Essen, Nordrhein-Westfalen, Germany

Levente Lippenszky

1Science and Technology Organization – Artificial Intelligence and Machine Learning, GE HealthCare, Budapest, Budapest, Hungary

Pablo Napan-Molina

3Science and Technology Organization – Artificial Intelligence and Machine Learning, GE HealthCare, San Ramon, CA, USA

Eszter Csernai

1Science and Technology Organization – Artificial Intelligence and Machine Learning, GE HealthCare, Budapest, Budapest, Hungary

Travis Osterman

2Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA

Balazs Laczi

1Science and Technology Organization – Artificial Intelligence and Machine Learning, GE HealthCare, Budapest, Budapest, Hungary

Alexander Brehmer

3Institute for AI in Medicine (IKIM), University Medicine Essen, Essen, Nordrhein-Westfalen, Germany

Moon Kim

3Institute for AI in Medicine (IKIM), University Medicine Essen, Essen, Nordrhein-Westfalen, Germany

Moritz Meyer

7Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Nordrhein-Westfalen, Germany

Stefan Kasper

5German Cancer Consortium (DKTK), Partner Site Essen, Essen, Nordrhein-Westfalen, Germany

Jens Kleesiek

3Institute for AI in Medicine (IKIM), University Medicine Essen, Essen, Nordrhein-Westfalen, Germany