Dataset on the synthesis and characterization of boron fenbufen and its F-18 labeled homolog
Chun-Nan Yeh,
Chi-Wei Chang,
Yi-Hsiu Chung,
Shi-Wei Tien,
Yong-Ren Chen,
Tsung-Wen Chen,
Ying-Cheng Huang,
Hsin-Ell Wang,
You-Cheng Chou,
Ming-Huang Chen,
Kun-Chun Chiang,
Wen-Sheng Huang,
Chung-Shan Yu
Affiliations
Chun-Nan Yeh
Department of Surgery, Liver Research Center, Chang-Gung Memorial Hospital at Linkou, Chang Gung University, Taiwan
Chi-Wei Chang
Department of Nuclear Medicine, Veterans General Hospital at Taipei, Taiwan
Yi-Hsiu Chung
Center for Advanced Molecular Imaging and Translation, Chang Gung Memorial Hospital, Taiwan
Shi-Wei Tien
Department of Biomedical Engineering and Environmental Sciences, National Tsinghua University, Hsinchu 300, Taiwan
Yong-Ren Chen
Department of Biomedical Engineering and Environmental Sciences, National Tsinghua University, Hsinchu 300, Taiwan
Tsung-Wen Chen
Department of Surgery, Liver Research Center, Chang-Gung Memorial Hospital at Linkou, Chang Gung University, Taiwan
Ying-Cheng Huang
Department of Neurosurgery, Chang-Gung Memorial Hospital at Linkou, Chang Gung University, Taiwan
Hsin-Ell Wang
Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan
You-Cheng Chou
Department of Biomedical Engineering and Environmental Sciences, National Tsinghua University, Hsinchu 300, Taiwan
Ming-Huang Chen
Department of Medical Radiology, Yang-Ming University at Taipei, Taiwan
Kun-Chun Chiang
Department of Surgery, Chang-Gung Memorial Hospital at Keelung, Chang Gung University, Taiwan
Wen-Sheng Huang
Department of Nuclear Medicine, Veterans General Hospital at Taipei, Taiwan
Chung-Shan Yu
Department of Biomedical Engineering and Environmental Sciences, National Tsinghua University, Hsinchu 300, Taiwan; Institute of Nuclear Engineering and Science, National Tsing-Hua University, Hsinchu 300, Taiwan
The data presented in this article are related to the research article entitled âSynthesis and Characterization of Boron Fenbufen and its F-18 Labeled Homolog for Boron Neutron Capture Therapy of COX-2 Overexpressed Cholangiocarcinomaâ. The contents of the data article include 1) the set up for performing in vitro binding assay, 2) 1H-, 13C- and 19F-NMR of compounds described in main text, 3) HPLC chromatogram of the fluorination mixtures, 4) data of in vitro stability test, cell survival assay, western blot and PCR analysis, 5) the modules for fixing the two CCA rats for BNCT, and 6) bar diagram for tumor reduction using [18F]FDG-PET 24Â h post treatment with BNCT. Keywords: Setup, NMR spectra, Coupling constant, Binding, Survival
